The uterus is a pear-shaped muscular organ whose inner lining (endometrium) grows each cycle under estrogen and progesterone to receive an embryo and sheds as menstruation if pregnancy does not occur.
Successful IVF depends mainly on patient age, embryo quality, and endometrial receptivity, with an ideal endometrial thickness of about 8–12 mm and a clear triple-line pattern on ultrasound.
Thin endometrium can be caused by infection (endometritis), low estrogen, poor blood flow, prior uterine surgeries, adhesions, or conditions like adenomyosis.
Endometrial receptivity is primarily evaluated with ultrasound, assessing thickness, pattern, volume, and blood flow.
Treatment options include lifestyle changes, hormonal therapy, hysteroscopic adhesiolysis, blood-flow–enhancing medicines, intrauterine growth factors, acupressure/acupuncture, and newer approaches like PRP or stem cell therapies, individualized to each patient.